- R. B. Budde, M. T. Williams, and P. P. Irazoqui, "Temporal interference current stimulation in peripheral nerves is not driven by envelope extraction," J. Neural Eng., Accepted Mar. 2023
- J. Shah, B. Collar, and P. P. Irazoqui, “An ASIC System for Closed-Loop Blood Pressure Modulation through Right Cervical Vagus Nerve Stimulation,” IEEE Tran. Biomedical Engineering, Accepted Mar. 2022.
- E. Biggs, R. Budde, J. G. R. Jefferys, and P. P. Irazoqui, “Carotid Body Stimulation as a Potential Intervention in Sudden Death in Epilepsy,” Major Revisions Feb. 2022.
- J. Shah, B. Collar, E. Ditslear, and P. P. Irazoqui, “A Highly Miniaturized, Chronically Implanted ASIC for Electrical Nerve Stimulation,” IEEE Tran. Biomedical Circuits and Systems, Accepted Feb. 2022.
- B. Collar, J. Shah, A. Cox, G. Simón, and P. P. Irazoqui, “Parylene-C Microbore Tubing: A Simpler Shunt for Reducing Intraocular Pressure,” IEEE Tran. Biomedical Engineering, Vol. 69, No. 3, pp. 1264-1272, Mar. 2022.
- R. Mandal, R. Budde, G. L. Lawlor, and P. P. Irazoqui, “Utilizing multimodal imaging to visualize potential mechanism for sudden death in epilepsy,” Epilepsy & Behavior, Vol. 122, Sep 2021.
- J. V. Shah, G. O. Albors, J. Williams, Q. Yuan, E. Milla, M. I. Firestone, G. Simon, and P. P. Irazoqui, “Clinical study of the IOPTx™ system - an electroceutical wearable to lower intraocular pressure,” Current Eye Research, Vol. 46, No. 10, pp. 1531-1538, Oct 2021.
- E. N. Biggs, R. B. Budde, J. G. R. Jefferys, and P. P. Irazoqui, “Ictal Activation of Oxygen-Conserving Reflexes as a Mechanism for Sudden Death in Epilepsy,” Epilepsia, Vol. 62, No. 3, pp. 752-764, Mar 2021.
- J. W. Tsai, M. P. Ward, P. P. Irazoqui, “A DSP Architecture for Distortion-Free Evoked Compound Action Potential Recovery in Neural Response Telemetry System,” IEEE Tran. Biomedical Circuits and Systems, Vol. 15, No. 1, pp. 29-42, Feb 2021.
- H. Bhamra, Y. W. Huang, Q. Yuan, P. P. Irazoqui, “An Ultra-Low Power 2.4 GHz Transmitter for Energy Harvested Wireless Sensor Nodes and Biomedical Devices,” IEEE Trans, Circ. & Syst. II, Vol. 68, No. 1, pp. 206-210, Jan 2021.
- R. B. Budde, D. J. Pederson, E. N. Biggs, J. G. R. Jefferys, P. P. Irazoqui, “Mechanisms and Prevention of Acid Reflux Induced Laryngospasm in Seizing Rats,” Epilepsy & Behavior, Vol. 111 Oct 2020.
- J. G. R. Jefferys, M. A. Arafat, P. P. Irazoqui, and T. A. Lovick, “Brainstem activity, apnea, and death during seizures induced by intrahippocampal kainic acid in anaesthetized rats,” Epilepsia, Vol 60, No 12, pp. 2346-2358, Dec 2019.
- B. Collar, G. Simon, Q. Yuan, S. Shen, P. P. Irazoqui, “Semi-Permanent Transcorneal Filter Support and in vivo Surgical Implantation Technique for Open-Angle Glaucoma Treatment,” Biomedical Microdevices, Biomed Microdevices, Vol. 21, No. 92, Nov 2019.
- M. A. Arafat, L. N. Rubin, J. G. R. Jefferys, and P. P. Irazoqui, “A Method of Flexible Micro-Wire Electrode Insertion in Rodent for Chronic Neural Recording and a Device for Electrode Insertion,” IEEE TNSRE, Vol. 27, No. 9, pp. 1724-31, Sep 2019.
- J. Somann, K. M. Wasilczuk, K. V. Neihouser, J. Sturgis, G. O. Albors, J. P. Robinson, T. L. Powley, and P. P. Irazoqui, “Characterization of Plasma Cytokine Response to Intraperitoneally Administered LPS & Subdiaphragmatic Branch Vagus Nerve Stimulation in Rat Model,” PLOS ONE, Vol. 14, No. 3, Apr 2019.
- O. Gall, C. Meng, H. Bhamra, H. Mei, S. John, P. P. Irazoqui, “A Batteryless Energy Harvesting Storage System for Implantable Medical Devices Demonstrated In-Situ,” Circuits, Systems, and Signal Processing Journal, Vol. 38, No. 3, pp. 1360-73, Mar 2019.
- K. M. Wasilczuk, K. Bayer, J. Somann, G. O. Albors, J. P. Robinson, P. P. Irazoqui, “Modulating the inflammatory reflex in rats using low intensity focused ultrasound stimulation of the vagus nerve,” Ultrasound in Medicine and Biology, Vol 45, No 2, pp. 481-489, Feb 2019.
- D. J. Pederson, C. J. Quinkert, M. A. Arafat, J. P. Somann, J. D. Williams, R. A. Bercich, Z. Wang, G. O. Albors, J. G. R. Jefferys, P. P. Irazoqui, “The Bionode: a closed-loop neuromodulation implant,” ACM Transactions on Embedded Computing Systems, Vol 18, No 1, Feb 2019.
- R. B. Budde, M. A. Arafat, D. J. Pederson, T. A. Lovick, J. G. R. Jefferys, P. P. Irazoqui, “Acid reflux induced laryngospasm as a potential mechanism of sudden death in epilepsy,” Epilepsy Research, Vol 148, pp. 23-31, Dec 2018.
- Y. J. Kim, K. R. Saviers, T. S. Fisher, P. P. Irazoqui, “Continuous glucose monitoring with a flexible biosensor and wireless data acquisition system,” Sensors & Actuators: B. Chemical, Vol 275, pp. 237-243, Dec 2018.
- D. S. Wie, Y. Zhang, M. Kim, B. Kim, S. Park, Y. J. Kim, P. P. Irazoqui, X. Zheng, B. Xu, C. H. Lee, “Wafer-recyclable, environment-friendly transfer printing for large-scale thin film nanoelectronics,” Proceedings of the National Academy of Science, Vol 115, No 31, Jul 2018.
- J. Somann, G. O. Albors, K. Neilhouser, K. H. Lu, Z. Liu, A. Durkes, J. P. Robinson, M. P. Ward, T. L. Powley, and P. P. Irazoqui, “Chronic Cuffing of Cervical Vagus Nerve Inhibits Efferent Fiber Integrity in Rat Model,” J. Neural Engineering, Vol 15, No 3, Apr 2018.
- C. Brouillard, J. Crook, P. P. Irazoqui, and T. Lovick, “Suppression of Urinary Voiding by Conditional High Frequency Stimulation of the Pelvic Nerve in Conscious Rats,” Frontiers in Physiology, Vol 9, pp 437, Apr 2018.
- K. Qing, K. M. Wasilczuk, M. P. Ward, E. H. Phillips, P. P. Vlachos, C. J. Goergen, P. P. Irazoqui, “B Fibers Are Best Predictors of Cardiac Activity During Vagus Nerve Stimulation,” Bioelectronic Medicine, Vol 4, No 5, Apr. 2018.
- K. A. Thackston, H. Mei, and P. P. Irazoqui, “Coupling Matrix Synthesis and Impedance Matching Optimization Method for Magnetic Resonance Coupling Systems,” IEEE Transactions on Microwaves Theory and Techniques, Vol 66, No 3, pp. 1536-1542, Mar 2018.
- J. Crook, C. Brouillard, P. P. Irazoqui, and T. Lovick, “Chronic implantation of cuff electrodes on the pelvic nerve in rats is well tolerated and does not compromise afferent or efferent fibre functionality,” J. Neural Engineering, Vol 15, No 2, Feb 2018.
- H. Bhamra, J. W. Tsai, Y. W. Huang, Q. Yuan, J. Shah, and P. P. Irazoqui, “A Sub-Cubic Millimeter Wireless Implantable Intraocular Pressure Monitor Microsystem,” IEEE Transactions on Biomedical Circuits and Systems, Vol 11, No 6, pp. 1204-1215, Nov 2017.
- H. Bhamra, J. Lynch, and P. P. Irazoqui, “A Noise-Power-Area Optimized Biosensing Front End for Wireless Body Sensor Nodes and Medical Implantable Devices,” IEEE Transactions on VLSI, Vol 25, No 10, pp. 2917-2928, Oct 2017.
- H. Mei, K. Thackston, R. Bercich, J. Jefferys, P. P. Irazoqui, “Cavity Resonator Wireless Power Transfer System for Freely Moving Animal Experiments,” IEEE Transactions on Biomedical Engineering, Vol 64, No 4, pp. 775-785, Apr 2017.
- R. A. Bercich, Z. Wang, H. Mei, L. H. Hammer, K. L. Seburn, L. J. Hargrove, P. P. Irazoqui, “Enhancing the versatility of wireless biopotential acquisition for myoelectric prosthetic control,” Journal of Neural Engineering, Vol 13, No 4, Aug 2016.
- J. Maeng, Y. J. Kim, C. Meng, P P. Irazoqui, “Three-Dimensional Microcavity Array Electrodes for High-Capacitance All-Solid-State Flexible Microsupercapacitors,” Applied Materials and Interfaces, Vol 8, No 21, pp. 13458–13465, May 2016.
- Y. Kim, D. Ha, W. J. Chappell, P. P. Irazoqui, “Selective Wireless Power Transfer for Smart Power Distribution in a Miniature-Sized Multiple-Receiver System,” IEEE Tran. Ind. Electronics, Vol 63, No 3, Mar 2016.
- H. Mei, Y. W. Huang, K. A. Thackston, P. P. Irazoqui, “Optimal Wireless Power Transfer to Systems in an Enclosed Resonant Cavity” IEEE Antennas and Wireless Propagation Letters, Vol 15, pp. 1036-1039 Mar. 2016.
- H. Bhamra, J. Joseph, J. Lynch, O. Z. Gall, H. Mei, C. Meng, J. Tsai, P. P. Irazoqui, “A 24 µW, Batteryless, Crystal-free, Multi-node Synchronized SoC "Bionode" for Wireless Prosthesis Control,” IEEE Journal of Solid State Circuits, Vol 50, No 11, pp. 2714-2727, Nov. 2015.
- Y. Kim, H. Bhamra, J. Joseph, P. P. Irazoqui, “An Ultra Low Power, RF Energy Harvesting Transceiver for Multiple Node Sensor Application,” IEEE Transactions on Circuits and Systems II, Vol 62, No 11, pp. 1028-1032, Nov. 2015.
- K. Qing, M. P. Ward, P. P. Irazoqui, “Burst-Modulated Waveforms Optimize Electrical Stimuli for Charge Efficiency and Fiber Selectivity,” IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol 23, No 6, pp. 936-945, Nov. 2015.
- Y. Kim, J. Maeng, P. P. Irazoqui, “Eyeglasses-Powered, Contact Lens-Like Platform with High Power Transfer Efficiency” Biomedical Microdevices, Vol 17, No 4, Aug. 2015.
- I. Dryg, K. Qing, M. P. Ward, H. Mei, J. Schaffer, P. P. Irazoqui, “Magnetically Inserted Neural Electrodes: Tissue Response and Functional Lifetime,” IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol 23, No 4, pp. 562-571, Jul. 2015.
- S. T. Lee, P. Williams, C. Braine, S. W. M. John, P. P. Irazoqui, “A Miniature, Fiber-Coupled, Wireless, Deep-Brain Optogenetic Stimulator,” IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol 23, No 4, pp. 655-664, Jul. 2015.
- V. Nagaraj, S. T. Lee, E. Krook-Magnuson, I. Soltesz, P. Benquet, P. P. Irazoqui, T. Netoff, “Future of Seizure Prediction and Intervention: Closing the Loop,” Journal of Clinical Neurophysiology, Vol 32, No 3, pp. 194-206, Jun. 2015.
- M. P. Ward, K. Qing, K. Otto, R. Worth, S. John, and P.P. Irazoqui, " A Flexible Platform for Biofeedback-driven Control and Personalization of Electrical Nerve Stimulation Therapy," IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol 23, No 3, pp. 475-484, May 2015.
- J. Maeng, C. Meng, P. P. Irazoqui, “Wafer-Scale Integrated Micro-Supercapacitors On An Ultrathin And Highly Flexible Biomedical Platform,” Biomedical Microdevices, Vol 17, No 1, Feb. 2015.
- H. Markandeya, P.P. Irazoqui, Kaushik Roy, “Low energy two-stage algorithm for high efficacy epileptic seizure detection,” IEEE Transactions on Very Large Scale Integration Systems, Vol 23, No 1, pp. 208-212, Jan. 2015.
- J. Lynch, P. P. Irazoqui, "A Low Power Logic-Compatible Multi-bit Memory Bit Cell Architecture with Differential Pair and Current Stop Constructs," IEEE Tran. on Circuits and Systems I, Vol 61, No 12, pp. 3367-3375, Dec. 2014.
- G. Xiong, C. Meng, R.G. Reifenberger, P. P. Irazoqui, and T.S. Fisher, " Graphitic Petal Micro-Supercapacitor Electrodes for Ultra-High Power Density," Energy Technology, Vol 2, pp. 897-905, Nov. 2014.
- H. Mei, P. P. Irazoqui,“Miniaturizing wireless implants,” Nature Biotechnology – News & Views, No. 32, pp. 1008-1010, Oct. 2014.
- C. Meng, J. Maeng, S. W. M. John, and P.P. Irazoqui, "Ultrasmall integrated 3D micro-supercapacitors solve energy storage on miniature devices," Advanced Energy Materials, May 2014.
- J. A. Wilden, K. Y. Qing, S. Hauser, W. J. McBride, P. P. Irazoqui, Z. A. Rodd, "Altering Neuronal Activity of the Nucleus Accumbens Shell by Pharmacological Silencing and Deep Brain Stimulation Reduces Oral Ethanol Consumption in Alcohol-Preferring (P) Rats." Journal of Neurosurgery, Vol 120, No 4, pp. 997-1005, Apr. 2014.
- E. J. Juan, R. Gonzalez, G. Albors, M. P. Ward, P. P. Irazoqui, “Vagus Nerve Modulation Using Focused Pulsed Ultrasound: Potential Applications and Preliminary Observations in a Rat” International Journal of Imaging Systems and Technology, vol. 14, no. 1, pp. 67-71, Mar. 2014.
- G. Xiong, C. Meng, R.G. Reifenberger, P.P. Irazoqui, and T.S. Fisher, "Graphitic petal electrodes for all-solid-state flexible supercapacitors," Advanced Energy Materials, vol. 4, no. 3, Feb. 2014.
- G. Xiong, C. Meng, R.G. Reifenberger, P.P. Irazoqui, and T.S. Fisher, "A review of graphene-based electrochemical micro-supercapacitors," ElectroanalysisJan. 2014.
- C. Meng, O. Z. Gall, and P. P. Irazoqui, "A flexible super-capacitive solid-state power supply for miniature implantable medical devices," Biomedical Microdevices, Vol 15, No 6, pp. 973-983, Dec. 2013.
- R. Bercich, D. R. Duffy, P. P. Irazoqui, “Far Field RF Powering of Implantable Devices: Safety Considerations,” IEEE Transactions on Biomedical Engineering, Vol. 60, No. 8, pp. 2107-2112, Aug. 2013.
- E. Y. Chow, M. M. Morris, P. P. Irazoqui, “Implantable RF Medical Devices,” IEEE Microwave Magazine, Vol. 14, No. 4, pp. 64-73, May 2013.
- D. Ha, W.N. de Vries, S.W. John, P.P. Irazoqui, W.J. Chappell, “Polymer-Based Miniature Flexible Capacitive Pressure Sensor for Intraocular Pressure (IOP) Monitoring Inside a Mouse Eye,” Biomedical Microdevices, Vol 14, No 1, pp. 207-215 Feb. 2012.
- S. Mrigank, S. K. Gupta, S. Raghunathan, P. P. Irazoqui, K. Roy, “Low-Power Architecture for Epileptic Seizure Detection Based on Reduced Complexity DWT,” ACM Journal on Emerging Technologies in Computing Systems (JETC) - Special Issue on Implantable Electronics, Vol 8, No 2, Jun 2012.
- A.L. Chlebowski, E.Y. Chow, C. Ellison, P.P. Irazoqui, “Integrated LTCC Packaging for Use in Biomedical Devices,” Bio-Medical Materials and Engineering, Vol. 22, No. 6, pp. 361-372, Jan. 2012.
- A. W. Conovaloff, B. L. Beier, P. P. Irazoqui, A. Panitch, “Effects of a synthetic bioactive peptide on neurite growth and nerve growth factor release in chondroitin sulfate hydrogels,” Biomatter, Vol. 1, No. 2, Dec. 2011.
- S. Raghunathan, A. Jaitli, P.P. Irazoqui, “Multi-Stage Seizure Detection Techniques Optimized for Low-Power Hardware Platforms,” Epilepsy & Behavior, Vol. 22, pp. S61-S68, Dec. 2011.
- E.Y. Chow, C.L. Yang, A. Chlebowski, S. Moon, P.P. Irazoqui, W.J. Chappell, “Wireless Powering and the Study of RF Propagation Through Ocular Tissue for Development of Implantable Sensors,” IEEE Transactions on Antennas & Propagation, Vol. 59, No. 6, pp. 2379-2387, Jun 2011.
- S. Raghunathan, S. Gupta, H. Markandeya, P.P. Irazoqui, Kaushik Roy, “Ultra Low-Power Algorithm Design for Implantable Devices: Application to Epilepsy Prostheses,” Journal of Low Power Electronics and Applications, Vol. 1, pp. 175-203, May 2011.
- P. Rajdev, M.P. Ward, and P.P. Irazoqui, “Effect of Stimulus Parameters in the Treatment of Seizures by Electrical Stimulation in the Kainate Animal Model,” International Journal of Neural Systems, Vol. 21, No. 2, pp. 151–162, Apr. 2011.
- M.S. Graves, T. Hassell, B.L. Beier, G.O. Albors, and P.P. Irazoqui, “Electrically Mediated Neuronal Guidance with Applied Alternating Current Electric Fields,” Annals of Biomedical Engineering, Vol. 39, No. 2, pp. 1759-1767, Feb. 2011.
- B.L. Beier, K.M. Musick, A. Matsumoto, A. Panitch, E.A. Nauman, and P.P. Irazoqui, “Toward a Continuous Intravascular Glucose Monitoring System,” Sensors, Special Issue on Biodevices and Materials, Vol. 11, pp. 409-424, Jan. 2011.
- E.Y. Chow, A. Chlebowski, P.P. Irazoqui, “A Miniature Implantable RF-Wireless Active Glaucoma Intraocular Pressure Monitor,” IEEE Transactions on Biomedical Circuits and Systems, Vol. 4, No. 6, pp. 340-349, Dec. 2010.
- A.R. Kahn, E.Y. Chow, O. Abdel-Latief, P.P. Irazoqui, “Low-Power, High Data Rate Transceiver System for Implantable Prostheses,” International Journal of Telemedicine and Applications, Vol. 2010, Nov. 2010.
- K.M. Musick, A.C. Coffey, and P.P. Irazoqui, “Sensor to Detect Endothelialization on an Active Coronary Stent,” BioMedical Engineering OnLine, Vol. 9, No. 67, Nov. 2010.
- S. Raghunathan, S.K. Gupta, H. Markandeya, K. Roy and P.P. Irazoqui, “A Critical Comparison of Seizure Detection Features for an Implantable Epilepsy Prosthesis,” Journal of Neuroscience Methods, Vol. 193, pp. 106-117, 2010.
- E.Y. Chow, A. Chlebowski, S. Chakraborty, W.J. Chappell, and P.P. Irazoqui, “Fully Wireless Implantable Cardiovascular Pressure Monitor Integrated with a Medical Stent,” IEEE Transactions on Biomedical Engineering, Vol. 57, No. 6, pp. 1487-1496, Jun. 2010.
- M.P. Ward and P.P. Irazoqui, “Evolving Refractory Major Depressive Disorder Diagnostic and Treatment Paradigms: Toward Closed-Loop Therapeutics,” Frontiers in Neuroengineering, Vol. 3, May 2010.
- P. Rajdev, M.P. Ward, R.M. Worth, J.L. Rickus, and P.P. Irazoqui, “Real-Time Seizure Prediction from Local Field Potentials using an Adaptive Wiener Algorithm,” Computers in Biology and Medicine, Vol. 40, No. 1, pp. 97-108, Jan. 2010.
- E.Y. Chow, Y. Ouyang, B. Beier, P.P. Irazoqui, W.J. Chappell, “Evaluation of Cardiovascular Stents as Antennas for Implantable Wireless Applications,” IEEE Transactions on Microwave Theory and Techniques, Vol. 57, No. 10, pp. 2523-2532, Oct. 2009.
- D.B. Jaroch, M.P. Ward, E.Y. Chow, J.L. Rickus, P.P. Irazoqui, “Magnetic Insertion System for Flexible Electrode Implantation,” Journal of Neuroscience Methods, Vol. 183, No. 2, pp. 213-222, Oct. 2009.
- E.Y. Chow, B. Beier, W.J. Chappell, P.P. Irazoqui, “Towards an Implantable Wireless Cardiac Monitoring Platform Integrated With an FDA Approved Cardiovascular Stent,” Journal of Interventional Cardiology, Vol. 22, No. 5, pp. 479-487, Oct. 2009.
- S.C. Schachter, J. Guttag, S. Schiff, D.L. Schomer, P.P. Irazoqui, et al., “Advances in the Application of Technology to Epilepsy: The CIMIT/NIO Epilepsy Innovation Summit,” Epilepsy & Behavior, Vol. 16, No. 1, pp. 3-46, Sep. 2009.
- S. Raghunathan, S.K. Gupta, M.P. Ward, R.M. Worth, K. Roy, P.P. Irazoqui, “The Design and Hardware Implementation of a Low-Power Real-Time Seizure Detection Algorithm,” Journal of Neural Engineering, Vol. 6, p. 056005, Aug. 2009.
- M.P. Ward, P. Rajdev, C. Ellison, P.P. Irazoqui, “Toward a Comparison of Microelectrodes for Acute and Chronic Recordings,” Brain Research, Vol. 1282, pp. 183-200, Jul. 2009.
- S.S. Jedlicka, M. Dadarlat, T. Hassell, Y. Lin, A. Young, M. Zhang, P.P. Irazoqui, J.L. Rickus, “Calibration of Neurotransmitter Release from Neural Cells for Therapeutic Implants,” International Journal of Neural Systems, Vol. 19, No. 3, pp. 197-212, Jun. 2009.
- E.Y. Chow, C.L. Yang, A. Chlebowski, S. Moon, W.J. Chappell, P.P. Irazoqui, “Implantable Wireless Telemetry Boards for in-vivo Transocular Transmission,” IEEE Transactions on Microwave Theory & Techniques, Vol. 56, No. 12, pp. 3200-3208, Dec. 2008.
- M. Rokkam, M.R. Chatni, A. ul Haque, A.R. DeCarlo, B.F. Robinson, P.P. Irazoqui, D.M. Porterfield, “High-Density Data Acquisition System and Signal Preprocessor for Interfacing with Microelectromechanical System-Based Biosensor Arrays,” Review of Scientific Instruments, No. 78, pp. 44303-44312, Apr. 2007.
- A. ul Haque, M. Rokkam, A.R. DeCarlo, S.T. Wereley, H.W. Wells, W.T. McLamb, S.J. Roux, P.P. Irazoqui, D.M. Porterfield, “A MEMS Fabricated Cell Electrophysiology Laboratory Biochip for In-silico Calcium Measurements,” Sensors and Actuators, Vol. 123, pp. 391-399, 2007.
- A. ul Haque, A.R. DeCarlo, M. Rokkam, S.T. Wereley, P.P. Irazoqui, H.W. Wells, W.T. McLamb, S.J. Roux, D.M. Porterfield, “Design, Fabrication and Characterization of an In Silico Cell Physiology Lab for Bio Sensing Applications,” Journal of Physics Conference Series, Vol. 34, pp. 740-746, 2006.
- P.P. Irazoqui, I. Mody, J.W. Judy, “Inductive Powering in Miniature Implantable Neural Recording Devices,” IEEE EMBS Magazine, pp. 48-54, Dec. 2005.